Total synthesis of calothrixin B via sequential Sonogashira coupling/copper-catalyzed oxidative cyclization.
نویسندگان
چکیده
A total synthesis of the antimalarial indolo[3,2-j]phenanthridine alkaloid calothrixin B is reported. The key intermediate, ketoester 11, was assembled using sequential Sonogashira coupling and intra/intermolecular fashioned copper-catalyzed oxidative cyclization reactions.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 13 45 شماره
صفحات -
تاریخ انتشار 2015